Senior Statistician

Merus N.V.
Cambridge
1 week ago
Applications closed

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Description

Merus is seeking a Senior/Principal Biostatistician with a robust background in statistics and relevant experience in clinical trials to join our team. To be based within our dynamic biostatistics function, you will be reporting to a Senior Director of Biostatistics. This position significantly impacts our clinical development activities, including leading the statistical aspects of clinical trials from design through to analysis, ensuring the delivery of high-quality data to support our clinical development programs.

Application Deadline: 25 July 2025

Department: Clinical Biostatistics

Location: Cambridge, MA

Description

Merus is seeking a Senior/Principal Biostatistician with a robust background in statistics and relevant experience in clinical trials to join our team. To be based within our dynamic biostatistics function, you will be reporting to a Senior Director of Biostatistics. This position significantly impacts our clinical development activities, including leading the statistical aspects of clinical trials from design through to analysis, ensuring the delivery of high-quality data to support our clinical development programs.

Your Role

As a Senior Biostatistician at Merus, you will be responsible for all statistical aspects of clinical trials, ensuring methodologies and analyses are robust and aligned with scientific objectives. Your role involves strategic collaboration with cross-functional teams and oversight of CROs to guarantee high-quality statistical deliverables.

Areas of responsibility:

  • Serve as the lead statistician for at least one study within our clinical development programs, offering strategic statistical input from trial design to analysis.
  • Collaborate with cross-functional teams on study design, including sample size, randomization procedures, endpoint selection, and case report form design.
  • Develop, oversee, and ensure the alignment of Statistical Analysis Plans (SAPs) with study objectives and regulatory compliance.
  • Oversee CRO deliverables, ensuring the accuracy, quality, and integrity of statistical outputs, including the production of tables, listings, and figures.
  • Foster collaborative relationships within the clinical department and with external vendors to maintain effective communication and project integrity.
  • Provide comprehensive statistical support across all phases of clinical trial and project development, including the design of clinical study reports.

Your Profile:

For this role, we seek a candidate with an advanced degree in statistics or equivalent, with relevant experience pharma, biotech or CRO. You'll bring a deep understanding of statistical principles applied to clinical research, proficiency in statistical software (e.g., SAS, R), and a proven ability to communicate complex statistical concepts clearly. Your expertise will be instrumental in driving our research forward, with strong knowledge of statistical principles in a regulatory environment .

Requirements:

  • A Master's degree in statistics or a related field, with at least 5 years of relevant experience in clinical trial analysis.
  • Demonstrated expertise in statistical analysis within clinical or related subjects - experience in oncology is a plus.
  • Familiarity with international standards (ICH, GCP, CDISC) and clinical study regulations.
  • Proficiency in statistical software packages (e.g., SAS, R).
  • Excellent communication and interpersonal skills, with the ability to translate complex statistical concepts for non-technical audiences.
  • Strong leadership and collaboration skills, capable of working on multiple projects simultaneously and under pressure.

Benefits

We offer a once-in-a-lifetime opportunity to work with some of the best and brightest in the biotech industry. As part of Merus, you’ll experience a steep learning curve from your very first day in the job. And you’ll get to interact with a great international team of people who love what they do! To top it all, we offer a competitive salary, flexible working hours, an excellent pension scheme, a company bonus and 30 days’ annual leave (based on a full-time position). Most importantly, you’ll have the chance to help us close in on cancer – everything you do matters at Merus.
Seniority level

  • Seniority levelMid-Senior level

Employment type

  • Employment typeFull-time

Job function

  • Job functionResearch, Analyst, and Information Technology

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