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Senior Biostatistician

Warman O'Brien
Sheffield
1 week ago
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Senior / Principal Biostatistician - CRO - UK/Remote


We have recently partnered with this modern thinking, CRO, who are looking for biostatisticians to join their team, to expand their outreach in the UK / Europe.


Key Accountabilities:

  • Work with a leader of the Statistical Operations management team to manage clinical trial programs/projects from one or multiple clients. Provide day to day technical and operational leadership to project teams supporting these programs/projects.
  • Provide statistical oversight on projects in the assigned drug development programs/projects, ensuring sound statistical methodologies in study design, sample size estimation, statistical analysis planning, statistical modeling, data handling, analysis, and reporting.
  • Coach, mentor, develop, and provide technical review, advice and expertise to less experienced Biostatisticians as well as Statistical Programmers assigned to the program/projects.
  • Provide statistical input in protocol design and development. Participate in the writing of trial protocols and research proposals.
  • Review and provide input to clinical data management deliverables, including but are not limited to the following: eCRFs, eCRF Completion Instructions, data validation specifications, Data Review Plan (and the ongoing data review tables, listings, and figures in accordance with the Plan), and Data Management Plan.
  • Write Statistical Analysis Plans, Statistical Reports, and statistical methodologies sections of Clinical Study Reports. Perform peer review of SAPs and other technical documents written by others.
  • Perform hands on statistical analysis and modeling, and maintains expertise in state-of-the-art statistical methodology and regulatory requirements.
  • Review and confirm ADaM dataset specifications. Perform quality control activities on ADaM datasets programmed by other statistical programmers and biostatisticians.
  • Provide statistical consultation to medical and clinical trial personnel for the publication of trial results, and participate in the writing of abstracts, manuscripts, posters, and presentations.
  • Ensure all study level as well as drug program level statistical and programming activities are conducted in compliance with relevant regulatory requirements
  • Interact with regulatory agencies and support sponsor in new drug application.
  • Contribute to organization development and growth by participating in the interview and evaluation process for professional applicants.


Qualifications and Experience:

A Ph.D. degree in statistical science, mathematical analysis or related fields

OR

A Master’s degree in the above fields


Interested? Drop me a message or send your CV to receive more details surrounding this role and discuss this further!

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