Postdoctoral Researcher, Quantitative Systems Pharmacology - Fixed Term Contract

Join GSK as a Postdoctoral Researcher in Quantitative Systems Pharmacology (QSP) within the Clinical Pharmacology and Quantitative Medicine (CPQM) group in Respiratory, Immunology and Inflammation Research Unit.

• Build mechanistic mathematical models of biological, physiological, and pathophysiological processes to evaluate disease, its pathways and progression as well as drug action to prevent, treat and cure diseases.
• Conduct simulations of virtual patients to inform target and/or asset prioritization and optimal trial design.
• Develop and/or utilize state‑of‑the‑art mathematical tools, including knowledge of non‑linear dynamics, scientific machine learning, and statistical techniques to gain insight into causal relationships between individual components of system‑level and drug‑level responses.
• Identify relevant questions by collaborating with disease area experts across disciplines and address them through mechanistic and systems modelling.
• Communicate and collaborate with clinicians, biologists, clinical pharmacologists, pharmacometricians, statisticians, AIML, imaging, biomarker, genomics scientists and other cross‑matrix colleagues to inform research and development programs and improve understanding of disease mechanisms.
• Promote transparency and communicate R&D achievements through publications in appropriate scientific journals.

• Ph.D., M.D., or Pharm.D. with experience in mechanistic modelling and simulation and systems biology.
• Strong drive to quickly learn and build knowledge on a drug‑disease system, including mechanism, endpoints, progression, prevention, treatments, and trial design.
• Strong communication skills and demonstrated ability to work in a multi‑discipline team, using effective communication and taking personal accountability for timely delivery of results.
• Prior experience in pharmaceutical research and development is a plus.
• Prior experience in respiratory (e.g. COPD, IPF), renal (e.g. CKD, nephrotoxicity), hepatology (e.g. MASH) and/or infection diseases (e.g. HBV) is a plus.

Closing Date for Applications – 7th of December, 2025 (COB).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.