Latest Isomorphic Labs Jobs

Software Engineer (Data Services), London

You will work as a software engineer on a cutting-edge AI-driven drug discovery platform, building and scaling data services that support scientific research and machine learning workflows. Your role involves designing robust data storage, integration, and serving systems, collaborating closely with scientists and ML researchers in a fast-paced, interdisciplinary environment. The position emphasizes innovation in data engineering and platform development to accelerate digital biology breakthroughs.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects by integrating medicinal chemistry expertise with AI-driven platforms. Guide projects from initiation to candidate selection, collaborate with machine learning teams to refine models, and manage CRO partnerships. The role emphasizes innovation in structure-based and fragment-based drug design within a dynamic, interdisciplinary environment.

Isomorphic Labs Cambridge, United Kingdom

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

Lead or contribute to computational drug design projects using AI-driven approaches, integrating machine learning into cheminformatics workflows. Guide drug discovery programs from hit identification through candidate selection, collaborating closely with ML scientists. Help shape and refine AI models while mentoring teams and driving innovation in molecular design and optimisation.

Isomorphic Labs Cambridge, United Kingdom

Senior Alliance Manager, London

This role involves managing strategic partnerships in the biotech and pharmaceutical space, focusing on advancing drug discovery through AI-driven innovation. The Senior Alliance Manager will oversee collaboration frameworks, governance, and joint research plans while fostering strong relationships between internal teams and external partners. The position requires deep expertise in alliance management, contract negotiation, and the drug development lifecycle, with an emphasis on operational excellence and value creation across long-term partnerships.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Bioinformatics Engineer, London

Build and maintain large-scale bioinformatics pipelines to transform raw biological data into standardized, ML-ready datasets. Collaborate with interdisciplinary teams to integrate high-quality, version-controlled data into AI-driven drug discovery workflows, ensuring robust and coherent biological insights. Drive adoption of best practices and platform-level solutions across research and development teams.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Head of Medicinal Chemistry, Drug Design, London

Lead a team of 25 medicinal chemists in redefining drug design through deep integration with AI/ML technologies. Provide strategic scientific leadership across the drug discovery pipeline, from hit identification to candidate nomination, while fostering collaboration with computational, biology, and pre-clinical teams. Shape and refine AI-driven platforms through expert feedback and champion innovative, AI-first approaches to accelerate therapeutic development.

Isomorphic Labs London, United Kingdom

On-site Permanent

ML Research Engineer, London

This role involves developing and optimizing cutting-edge AI models at the intersection of machine learning and drug discovery. You'll work in a collaborative, interdisciplinary environment to translate research concepts into scalable, high-performance systems, focusing on foundational models like Transformers, GNNs, and Diffusion models. The position emphasizes innovation in computational biology and chemistry, with a strong focus on robust codebases, data pipelines, and full lifecycle ML development.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Scientist (Applied LLMs), London

A Research Scientist will apply Large Language Models to drug discovery challenges, developing novel ML techniques and collaborating with interdisciplinary teams. The role involves pushing the boundaries of LLMs on biological and medical data, refining models, and contributing to a culture of innovation in AI-driven drug design.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Research Scientist (Machine Learning), London

A Research Scientist in Machine Learning will develop novel deep learning models and algorithms to advance drug discovery, working collaboratively with interdisciplinary teams of scientists and engineers. The role involves designing architectures, training models, and applying AI to biological and chemical challenges, with opportunities to lead projects and mentor others depending on experience.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Software Engineer (TechOps), London

You will work on a groundbreaking platform that transforms the biopharmaceutical world, partnering with engineers, scientists, and ML researchers to build cloud infrastructure and software lifecycle tools. Your role involves designing, operating, and refining cloud infrastructure, developing tools for software development, and contributing to core technical decisions.

Isomorphic Labs United Kingdom

Hybrid Permanent

Bioanalytical Lead, London

Lead the bioanalytical strategy for AI-designed therapeutic candidates across small molecules, biologics, and ADCs, from discovery through preclinical development. Design and validate PK, PD, and immunogenicity assays, manage global CROs, and integrate wet-lab data back into AI models to improve predictive accuracy. Play a key role in IND-enabling studies and cross-functional teams, ensuring regulatory compliance and scientific innovation in a hybrid London-based role.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Security Engineering Manager, London or Lausanne

Lead and scale a security engineering team at the forefront of AI-driven drug discovery, designing and implementing a robust, AI-first security architecture for a digital biology platform. Collaborate with ML researchers and medical teams to enable secure, high-velocity innovation while managing cloud security, incident response, and enterprise-scale transformation projects in a hybrid environment.

Isomorphic Labs United Kingdom

Associate Director, Clinical Program Management, Cambridge, MA

The role involves leading the transition of internal drug programs from pre-IND stages into clinical trial execution, managing cross-functional teams, timelines, budgets, and vendor partnerships. The Clinical Program Manager will ensure alignment between clinical objectives and company goals, leveraging AI and emerging technologies to drive efficient, high-success clinical development across a global, interdisciplinary environment.

Isomorphic Labs England

Hybrid Permanent

General Application - Register Your Interest

This is a general interest registration for roles at Isomorphic Labs, an AI-driven drug discovery company building advanced predictive and generative models to accelerate the development of novel medicines. The interdisciplinary team works at the intersection of machine learning and biology, aiming to transform drug design across multiple therapeutic areas. Candidates from software engineering, ML research, computational chemistry, and technical program management backgrounds are encouraged to express interest.

Isomorphic Labs United Kingdom

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

This role involves providing medical leadership for oncology clinical trials, translating AI-driven insights into clinical development strategies, and ensuring patient safety and regulatory compliance. The Medical Director will lead cross-functional teams, serve as primary medical monitor, and guide regulatory submissions and interactions with health authorities and key opinion leaders. Based in Cambridge, MA, the position operates at the intersection of AI-driven drug discovery and clinical development in oncology.

Isomorphic Labs England

Hybrid Permanent