Latest Isomorphic Labs Jobs

Head of Medicinal Chemistry, Drug Design, London

As Head of Medicinal Chemistry, you will lead a team of 25 chemists in London, driving the development of novel drugs using cutting-edge AI and machine learning. You will provide strategic direction, mentor team members, and collaborate closely with AI/ML scientists to accelerate drug discovery and clinical candidate nomination.

Isomorphic Labs London, United Kingdom

On-site Permanent

Senior Research Investigator, (Biologics Pharmacology), London

As a Senior Research Investigator, you will play a pivotal role in the pharmacology and translational biology strategy for novel large molecule therapeutics. You will design and execute comprehensive pharmacology plans, lead in vivo and in vitro evaluations, and collaborate with interdisciplinary teams to advance candidates from early discovery to clinical stages using cutting-edge AI and ML technologies.

Isomorphic Labs London, United Kingdom

On-site Permanent

Bioanalytical Lead, London

This role involves leading bioanalytical strategy for AI-designed drug candidates across small molecules, biologics, and ADCs, from discovery through preclinical development. The candidate will design and validate PK, PD, and immunogenicity assays, manage global CROs, integrate bioanalytical data into AI models, and support regulatory submissions including INDs. A key focus is bridging computational discovery with wet-lab execution in a fast-paced, interdisciplinary environment.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

Lead clinical development strategy for oncology programs, translating AI-driven insights into actionable trial designs and guiding assets from discovery through proof-of-concept. Serve as medical monitor and primary clinical liaison, ensuring scientific rigor, regulatory compliance, and patient safety across cross-functional teams and global health authority interactions.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Head of Chemistry, Drug Design, Cambridge, MA

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs Cambridge, United Kingdom

Head of Computational Drug Design, Cambridge, MA

Leads the Computational Drug Design team in advancing AI-driven drug discovery, integrating machine learning with computational chemistry to accelerate the development of novel therapeutics. Oversees project delivery from hit identification to candidate nomination, mentors a team of computational chemists, and collaborates across AI, biology, and medicinal chemistry functions. Plays a key role in shaping strategy, guiding external partnerships, and embedding AI into rational drug design workflows.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Medicinal Drug Design Lead, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Research Scientist (Applied LLMs), London

This role involves developing and refining large language model (LLM) applications to accelerate drug discovery, working in close collaboration with interdisciplinary scientists. The Research Scientist will innovate on model architectures, apply LLMs to complex biological challenges, and contribute to a cutting-edge AI-driven drug design platform. The position emphasizes technical leadership, experimentation, and cross-disciplinary iteration to advance digital biology.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Team Leader, Medicinal Drug Design, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Team / Research Leader, Computational Drug Design, London

This role involves leading the design of novel small molecule therapeutics using cutting-edge AI and machine learning techniques. You will define the scientific direction, manage drug discovery programs, and mentor a high-performing team of computational chemists.

Isomorphic Labs United Kingdom

Hybrid Permanent

Head of Translational Sciences, Drug Design, Cambridge, MA

You will lead the Translational Science strategy, identifying biomarkers and developing assays to guide clinical paths and patient selection. You'll ensure scientific rigor, partner with the VP of Drug Discovery to build a top-tier team, and collaborate with the London team to maintain unified standards. Your role involves managing in vitro and in vivo biology operations through CROs and fostering a culture of accountability and rapid iteration.

Isomorphic Labs Cambridge, United Kingdom

On-site Permanent

PKPD Modelling Lead, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Software Engineer (HPC Platform), London

As a Software Engineer focused on GPU infrastructure, you will play a key role in designing, optimizing, and managing the large-scale AI/ML infrastructure that powers Isomorphic Labs' groundbreaking research. You will collaborate with machine learning experts, biotech researchers, and cross-functional teams to ensure the reliability and efficiency of our AI models and cloud infrastructure.

Isomorphic Labs London, United Kingdom

On-site Permanent

DMPK Lead, London

As a DMPK Lead, you will drive the DMPK strategy for drug discovery projects, integrating quantitative pharmacology and AI models to deliver high-quality clinical candidates. You will collaborate with interdisciplinary teams to design and implement stage-appropriate DMPK strategies, optimize the use of datasets, and support project progression through data-driven decision-making.

Isomorphic Labs United Kingdom

Hybrid Permanent

Team / Research Leader (Translational Oncology), London

This role involves leading the development and execution of comprehensive translational strategies for Isomorphic Labs' oncology pipeline. You will collaborate with interdisciplinary teams, manage a group of biologists, and ensure the successful transition of AI-designed drugs from preclinical to clinical stages, focusing on biomarker and patient selection strategies.

Isomorphic Labs United Kingdom

Hybrid Permanent