Senior Scientist – UPLC Triple Quadrupole

Senior Bioanalytical Scientist - Triple quadruple MS - biotech in London

We are seeking a Senior Bioanalytical Scientist with proven expertise in UPLC coupled with triple quadrupole mass spectrometry (ESI), to join a small biotech in London. This is a hands-on, lab-based position in a fully regulated environment supporting high-integrity, high-sensitivity bioanalytical work.

Industry: biotech

Location: On-site in London

Employment Type: Full-time, Permanent

Key Responsibilities:

• Operate, maintain, and troubleshoot UPLC-MS/MS instrumentation (ideally Waters)
  
  
• Develop and validate robust, sensitive bioanalytical methods for complex biological matrices
  
  
• Perform quantitative analysis in accordance with GLP/GCLP and sponsor-specific protocols
  
  
• Ensure data quality, reproducibility, and full compliance with regulatory documentation standards
  
  
• Contribute to the delivery of client projects within a collaborative, scientifically rigorous environment
  
  Essential Requirements:
  
  
• Demonstrable experience with UPLC and triple quadrupole mass spectrometry using electrospray ionization (ESI)
  
  
• Hands-on use of Waters systems (e.g., Xevo TQ, MassLynx) is highly desirable
  
  
• Familiarity with GLP and/or GCLP requirements and regulated laboratory workflows
  
  
• Strong understanding of method development, sample preparation, and assay validation
  
  
• Must have the right to work in the UK
  
  Qualifications:
  
  
• Degree in a scientific field
  
  
• Postgraduate qualification (MSc/PhD) is preferred but not required if supported by substantial practical experience
  
  This is an excellent opportunity to join a specialist clinical laboratory contributing to essential drug development and translational science. Candidates who value scientific precision, regulatory compliance, and team collaboration will thrive in this role