Scientist - Multiomics

Oxford
1 month ago
Applications closed

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We're hiring for an exciting opportunity in the life sciences sector for a Scientist I/II to join a pioneering team advancing the next generation of mammalian cell expression systems. This role is ideal for candidates passionate about applying multi-omics approaches to gene target discovery, with a strong foundation in cell biology, molecular techniques, and omics-based data analysis. You'll contribute to projects shaping more efficient and cost-effective immunotherapeutic production processes.

About the Role

As a key member of a collaborative and multidisciplinary research team, you’ll design and execute multi-omics workflows that fuel innovation in gene discovery and cell line engineering. Your expertise will drive characterisation efforts, contribute to hypothesis generation, and influence experimental designs involving CRISPR and ORF libraries. This is a hands-on lab role where your ability to optimise, interpret, and communicate scientific findings will be central to your success.

Key Responsibilities

Design and perform experiments to generate and analyse multi-omics datasets (transcriptomics, proteomics, metabolomics).

Support gene/pathway discovery and development of predictive models using in silico tools.

Develop and optimise high-throughput sample preparation protocols for omics applications.

Conduct mammalian suspension cell culture, banking, nucleofection, and molecular assays (e.g. western blotting, FACS).

Document research findings and contribute to scientific presentations and internal reporting.

Maintain lab records, health and safety standards, and support shared lab responsibilities.

Train team members to uphold data integrity and contribute to a culture of continuous improvement.

About You

You’ll bring a mix of scientific expertise, curiosity, and collaborative spirit. Whether from an academic or industry background, you’re excited to apply your omics and molecular biology skills to real-world bioprocess challenges.

Required Qualifications and Experience:

MSc with 5+ years of industry experience or PhD with 2+ years of industry experience in Biochemistry, Molecular Biology, or a related field.

Hands-on experience with transcriptomic, proteomic, or metabolomic data generation and interpretation.

Skilled in CRISPR/ORF library experiments and mammalian cell line development (e.g. CHO cells).

Familiar with molecular biology techniques: FACS, qRT-PCR, Western Blot, ELISA.

Comfortable working independently and collaboratively, with strong experimental planning and troubleshooting abilities.

Desirable:

Knowledge of metabolic flux analysis (MFA).

Experience applying Design of Experiments (DoE) methodologies.

Skills and Attributes

Innovative and analytical thinker

Strong communication and documentation skills

Organised and adaptable, with excellent time management

Proactive, collaborative, and committed to continuous learning

Salary: £35k - £40k

Oxford

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