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Principal Scientist - Bioanalysis (Quantitative Mass Spectroscopy

Pharmaron
Northamptonshire
5 days ago
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We are looking for:

We are seeking a highly skilled and experienced Senior Technical Specialist in Quantitative Mass Spectroscopy to join our dynamic team. In this role, you will leverage your deep expertise in quantitative LC-MS/MS to lead the development, validation, and troubleshooting of analytical methods for regulated bioanalysis. You will play a critical role in ensuring the accuracy, reliability, and compliance of our analytical processes, supporting a wide range of studies across the department. This is an exciting opportunity to contribute to cutting-edge scientific work in a fast-paced, collaborative environment, where your technical leadership will directly impact the success of our projects and the advancement of our capabilities.

At Pharmaron we offer:

Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!

Key roles and responsibilities:

Perform complex method development on large and small molecules. Provide analytical trouble shooting support across the department, as required. Responsible for technical training (writing and review of training materials) and maintenance of laboratory work standards in their area. Mentor new Technical Specialists and other senior laboratory staff. Perform routine sample analysis, as required. Review data obtained and prepare study updates and study data for discussion internally and for communication to the client. Effectively communicate with clients regarding study progress and address client comments. Identify new technologies, which could be of significant benefit to the group, improving capability or reducing operational costs. Lead process improvement/new service development projects in their specialist area Act as an interface with contract service support provider for LC-MS/MS, calling engineers and managing instrument break-downs to ensure minimum instrument down-time. Maintain and write SOPs, as required. As a recognised expert in Bioanalysis increase the profile of the department externally through playing an active role in expert groups, networking and publications improvement/new service offering initiatives to the Metabolism leadership team. Review proposals ensuring all costs are included and revenue recognition milestones are clear. Actively participate in and where necessary lead client facility visits.

Requirements:

PhD, MSc or BSc (Hons) in Chemistry or related subject Many years’ experience of regulated small and large molecule bioanalysis including method development and validation of LC-MS methods and trouble shooting in a CRO or Pharmaceutical Company. Extensive experience of using quantitative Mass Spectrometers e.g. Sciex 6500 Recognised expert in Bioanalysis with deep knowledge of the of development and validation of quantitative LC-MS methods Proficient in the use of relevant software e.g. Analyst and Watson Thorough understanding of the regulated bioanalysis guidelines Scientific data interpretation, reporting and presentation skills Effective written and verbal communication skills, including the ability to effectively present scientific

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