Postdoctoral Fellow - Computational

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges.

Our lab aims to understand how the lung microbiome contributes to chronic lung disease. We combine advanced airway sampling and dense longitudinal collection with state of the art ‘omic approaches to accurately describe the ecology of the respiratory microbiome in both space and time to define causal relationships to lung pathobiology.

We are seeking aPostdoctoral Researcher in Bioinformaticsto support cutting-edge projects at the interface of host-microbiome interactions, spatial transcriptomics, and metagenomics.

You will be responsible for:

• Develop and apply computational methods for analysingspatial transcriptomics,host transcriptomics, and bacterialmetagenomicdatasets.
• Integrate multi-omics data to investigate host-microbiome interactions
• Work closely with experimental biologists to process and interpret high-throughput sequencing data.
• Contribute to manuscript writing and presentations at scientific conferences.
• Support the training of PhD students and researchers in bioinformatics techniques

About You:

We are looking for an ambitious individual who wants to lead projects and develop their own ideas. You will be expected to be an active member of the team and collaborate with other teams inside and outside of the institute.

Essential Technical Skills:

• PhD in relevant subject area, or on track to be awarded your PhD within 6 months of starting the role
• Proven ability to deliver research projects
• A track record of demonstrating research excellence and expertise in your area of research
• The ability to analyse and interpret genomic and transcriptomic data with strong quantitative/computational skills
• Programming and bioinformatics skills
• Strong programming skills (Python, R, Bash, or similar) and experience with high-performance computing.
• Expertise in analysing next-generation sequencing (NGS) data, particularly single-cell or spatial transcriptomics, bulk transcriptomics or bacterial metagenomics

Essential Competencies and Behavioural Skills:

• Proven ability to develop and maintain effective working relationships with a wide range of persons of differing levels, abilities and knowledge
• Foster an inclusive culture where all can thrive and diversity is celebrated
• Team player with the ability to work with others in a collegiate and collaborative environment
• Ability to effectively communicate ideas and results and present orally to groups
• Commitment to personal development and updating of knowledge and skills
• Ability to prioritise, multi-task and work independently
• Detail-oriented, strong organizational and problem-solving skills

About Us:
This position would place you within Dr Josie Bryant’s team within the Parasites and Microbes Programme, set within a world-leading genomics institute. You would be working closely with informaticians, wet-lab biologists, Postdoctoral Fellows and PhD students within the group and across this programme. You will be required to coordinate analysis of multiple project datasets and identify and establish new collaborations and projects, as well as to form part of an integrated team. You will have substantial support and opportunities to broaden your skill-set and further your career.

When you join us as a Postdoctoral Fellow, you will benefit from a unique and well-resourced learning environment that will equip you for your future career.

Please apply with your CV and a Cover Letter outlining how you would meet the criteria set out above.

Recruitment Process:Shortlisting w/c 21st April, Interviews 29th April

Contract Type:3 years Core funding

We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.

Equality, Diversity and Inclusion:

We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness. The networks are also a place for allies to provide support to others.

We want our people to be whoever they want to be because we believe people who bring their best selves to work, do their best work. That’s why we’re committed to creating a truly inclusive culture at Sanger Institute. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme. The importance of good health and adopting a healthier lifestyle and the commitment to reduce work-related stress is strongly acknowledged and recognised at Sanger Institute.

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