4,000 professionals, 0 days wasted, 1 incredible purpose. Together, we are beating cancer.

Lead Statistician (Oncology Drug Development)

Salary: £75,000 - £90,000 pa depending on experience + benefits

Reports to:Chief Drug Development Scientist

Department:Research & Innovation

Contract: Permanent

Hours: Full time 35 hours per week (other flexible-working requests will also be considered if it meets business needs

Location:Stratford, London (High flex – we’d expect you to be in the office 1 or 2 days a month).

Application Deadline:Sunday 2nd February at 23.59. This vacancy may close earlier if a high number of applications are received or once a suitable candidate is found, so please do not delay submitting your application to avoid any disappointment.

At Cancer Research UK, we exist to beat cancer

We are professionals with purpose, beating cancer every day. But we need to go much further and much faster. That’s why we we’re looking for someone talented, someone innovative and ambitious, someone like you.

We have a new, exciting opportunity for aLead Statisticianto join our Centre for Drug Development (CDD).

About the team

The Cancer Research UK Centre for Drug Development (CDD) is a team of around 100 staff with core skills in early phase drug development. The CDD sits at the heart of the charity’s innovation network of Experimental Cancer Medicine Centres and serves as a pivotal enabler for the translation of novel therapeutic concepts from bench to bedside. We are now set to embark on an exciting period of growth and strategic evolution that will underpin our ambition to become the ‘go-to’ European centre for drug development in the non-commercial sector. We have recently put in place collaborative agreements with likeminded funders of cancer research, the Dutch Cancer Society (KWF) and the Norwegian Cancer Society (NCS) to support joint efforts in translating research into real patient benefit.

What will you be doing?

We have created a new role for an experienced statistician to act as a strategic partner for project teams in providing statistical expertise for the design, conduct, delivery and reporting of CDD-sponsored clinical trials. You will be joining at a pivotal moment in the evolution of the CDD and this role offers an opportunity to play a key role in shaping the design of early phase clinical trials investigating a broad range of next generation therapeutics.

Key responsibilities include:

• To secure statistical expertise for study design, protocol development and delivery of CDD-sponsored clinical trials.
• Ensure a consistent approach is taken across the CDD trial portfolio by acting as the primary point of contact for project teams with external statisticians.
• Preparation of requests for proposals for statistical support from external vendors/consultants and lead on review and selection.
• Where appropriate fulfil the role of trial statistician for CDD-sponsored clinical studies.
• Liaise with relevant functions to support the operational delivery of clinical studies including development of statistical analysis plans and electronic case report forms.
• Provision of statistical input into the preparation of clinical study reports and trial publications.
• Review and QC of agreed deliverables from biostatistics vendors/collaborators (e.g. statistical analysis plans, protocol sections, reports).
• Communicate and ensure compliance of vendors and other relevant third parties with CDD SOPs and working practices.
• To demonstrate a commitment to the importance of increasing equality, diversity and inclusion in CRUK’s drug development and clinical trial portfolio.

What expertise are we looking for?

Essential

• Extensive experience of working as a trial statistician for early phase oncology studies, including first-in-human trials.
• Comprehensive knowledge of statistical methodology including frequentist and Bayesian methods
• Excellent understanding of oncology drug development including current and emerging treatment paradigms and incorporation of clinical and translational endpoints.
• Fluency in statistical programming language e.g. R or Stata.

Desirable

• Experience of working in the pharma or biotech sector
• PhD in Statistical Science
• Late phase development experience.

What will I gain?

We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals.

You can explore our benefits by visiting our careers web page.

How do I apply?

We operate an anonymised shortlisting process in our commitment to equality, diversity, and inclusion. CVs are required for all applications; but we won’t be able to view them until we invite you for an interview. Instead, we ask you to complete the work history section of the online application form for us to be able to assess you quickly, fairly, and objectively.

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Please note: Cancer Research UK can consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application.