ICON PLC - Principal Biostatistician

Promoting Statistical Insights
Sheffield
1 day ago
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ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.


As a Principal Biostatistician, you will lead the statistical strategy and delivery for Phase I–III oncology trials. You will serve as a key expert across protocols, SAPs, data analysis, and regulatory submissions while mentoring others and driving process improvement.


About the role

Principal Biostatistician, Office or Home, India


Key Responsibilities

  • Lead statistical strategy and execution for oncology programs and individual studies
  • Review protocols, SAPs, and clinical reporting to ensure scientific and regulatory excellence
  • Provide statistical guidance to clients and support agency interactions
  • Perform and oversee inferential analyses using SAS and/or R
  • Contribute to proposals, bid defenses, and client presentations
  • Mentor junior statisticians and support continuous process improvement initiatives

Your Profile

  • Master’s degree or PhD with 10+ years of experience in biostatistics or a related discipline
  • Strong experience leading Phase I–III oncology studies and client engagements
  • Hands‑on programming skills in SAS and/or R
  • Knowledge of regulatory processes including support for submissions
  • Excellent communication and leadership capabilities with strong prioritization skills
  • Experience in a CRO environment preferred

What ICON can offer you

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits designed to be competitive within each country and focused on well‑being and work‑life balance opportunities for you and your family.



  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead
  • Global Employee Assistance Programme, LifeWorks, offering 24‑hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well‑being
  • Life assurance
  • Flexible country‑specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others

How to Apply

Please click here to apply!


Statisticians in the Pharmaceutical Industry Executive Office:
St James House | Vicar Lane | Sheffield | S1 2EX | UK


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