HTA Evidence Synthesis Statistician

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We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize sharing our enterprise strategies while remaining focused on addressing the unique country’s needs as a value‑added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio.

An opportunity has arisen for an experienced Senior HTA Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA). This role offers the chance to lead the evidence synthesis of patient data from clinical, observational, and real‑world data studies supporting HTA submissions, in a flexible and collaborative environment. The role is responsible for leading the design and execution of evidence‑synthesis for HTA submissions incl. EU HTA JCA Dossier and for health economic models. Position applies methodological and analytical expertise to predict the value of Novartis assets and develop strategies on how best to demonstrate this to external decision makers. Role will strategically and effectively communicate, and tailor generated evidence to multiple stakeholder audiences.

• Develop core global Indirect Treatment Comparison (ITC) plan for HTA, payer and other Access stakeholder assessments, submissions, and negotiations. Lead publications associated with these to meet business objectives.
• Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the Indirect Treatment Comparison (ITC) for local HTA submissions and support the local assessment of HTA strategy. Coordinate data requirements across evidence generation functions (Clinical Development; Medical Affairs/Biostat and HEOR & PCO) to support Pricing & Reimbursement.
• Set‑up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables e.g., statistical analysis plans. Track key HTA statistics priorities and sequence them aligning with resource availability and risks.
• Identify need for preliminary ITCs to inform value proposition, development, pricing and commercial strategic forecast and decisions.
• Lead and facilitate the sharing of best practices and key learnings across regions, countries and cross‑functional partners.
• Stay on top of innovative techniques, using robust analytical techniques leveraging available clinical data and published information to inform pricing and market access strategy.
• Collaborate with the MA Biostats team for trial analyses, HTA challenges, and statistical analyses.
• Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access (Therapeutic Area Access, Pricing) to ensure alignment to brand and commercial, access and evidence strategy. Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers and publications.
• Provide mentoring and coaching support to junior members of evidence modelling teams and across function.

• MSc/PhD in Statistics, Biostatistics, or a related field. Experience from pharmaceutical industry or life‑science consultancy.
• 6‑8 years relevant experience in consultancy or pharmaceutical industry in Evidence Synthesis, Health Economics, Health Technology Assessment, or related area.
• Strong understanding of clinical drug development and HTA‑related regulations and processes.
• Local HTA experience including experience with country HTA submissions.
• Strong understanding of statistical methodologies for indirect treatment comparisons (ITCs) and population‑adjusted indirect comparison (PAIC).
• Proficiency in statistical software such as R and/or SAS.
• Strong interpersonal and scientific communication skills. Excellent problem‑solving abilities and attention to detail.
• Ability to lead in a matrix environment and work collaboratively in interdisciplinary cross‑functional teams.

This role can be based in the UK, London but also based in Basel, Switzerland and Dublin, Ireland.

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Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Novartis is committed to working with and providing reasonable accommodation to all individuals. If, due to a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e‑mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture