Genomic Data Scientist

Canary Wharf
1 week ago
Create job alert

Company Description

Genomics England partners with the NHS to provide whole genome sequencing diagnostics. We also equip researchers to find the causes of disease and develop new treatments – with patients and participants at the heart of it all.

Our mission is to continue refining, scaling, and evolving our ability to enable others to deliver genomic healthcare and conduct genomic research.

We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Job Description

We are seeking a Genomic Data Scientist to join our Bioinformatics Consulting team to work on a range of genome analysis and interpretation projects with an emphasis in rare or complex disease, in collaboration with and on behalf of our external researchers and industrial partners.  

In this role, you will work as part of multidisciplinary teams to develop and execute cutting edge projects that leverage Genomics England datasets to address research goals such as drug target identification, biomarker discovery, diagnostic discovery, and patient stratification. 

You will contribute to the scoping, implementation, and application of state-of-the-art approaches for analysis of genomic and other omics modalities, in both leading and supporting capacity. As an expert user of our datasets and research environment, you will develop and fine-tune tools and pipelines to perform custom computational analyses, generate new data and contribute to high quality reports and documentation. 

Everyday responsibilities include: 

Preparing data for downstream analysis, e.g. through quality control, functional annotation, aggregation, harmonisation across different datasets. 
Planning and supporting analyses to meet project objectives with internal teams and external stakeholders. Providing support to internal teams and collaborators and being the point of reference for genomic datasets and analytical approaches. 
Performing custom computational analyses on whole genome sequencing and other omics data, such as GWAS, aggregate variant testing, meta-analysis, differential abundance, fine-mapping and MR. 
Researching the scientific literature, identifying new approaches to processing and analysis of genomics and multi-omics data, benchmarking and improving tools.
Contributing to the publication and dissemination of findings via scientific papers, white papers and conference presentations. Skills and Experience for Success:

Strong programming skills (R, Python) and solid background of statistical genetics.
Demonstrable experience using whole genome sequencing data in the context of human genetics.   
Strong background in human disease genetics, preferably in rare or complex disease, demonstrated by publication record or industry track record. 
Demonstrable experience with at least one additional omics modality (e.g. long read sequencing, single cell transcriptomics, proteomics, metabolomics).
Proven track record in one or more areas of human germline DNA analysis such as genetic association testing, population genetics, pharmacogenomics, rare disease genomics, structural variation analysis, working with complex genomic regions such as HLA/KIR/PGx. 
Experience with working in the cloud, building containers, and running pipelines in nextflow.  
Proven ability to communicate with stakeholders from diverse backgrounds (e.g. management, IT, R&D, biology, bioinformatics) and keep track of customer relationships, and a clear understanding of clinical and phenotypic data management and the sensitivities surrounding patient cohort data. 
Excellent interpersonal skills, attention to detail, self-motivation, collaborative and delivery mindset  

Qualifications

A PhD involving one of the following: Statistical or Computational Genetics, Biostatistics, Population Genetics or equivalent quantitative discipline. 

Additional Information

Salary from £55,000

Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including: 

Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).
Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.
Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), and a Give As You Earn scheme.
Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).
Recognition & Rewards: Employee recognition programme and referral scheme.
Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.Equal opportunities and our commitment to a diverse and inclusive workplace 

Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. 

Genomics England’s policies of non-discrimination and equity and will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part-time or employed under a permanent or a fixed-term contract or any other relevant factor.  

Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour is contrary to

Get the latest insights and jobs direct. Sign up for our newsletter.

By subscribing you agree to our privacy policy and terms of service.

Industry Insights

Discover insightful articles, industry insights, expert tips, and curated resources.

Portfolio Projects That Get You Hired for Data Science Jobs (With Real GitHub Examples)

Data science is at the forefront of innovation, enabling organisations to turn vast amounts of data into actionable insights. Whether it’s building predictive models, performing exploratory analyses, or designing end-to-end machine learning solutions, data scientists are in high demand across every sector. But how can you stand out in a crowded job market? Alongside a solid CV, a well-curated data science portfolio often makes the difference between getting an interview and getting overlooked. In this comprehensive guide, we’ll explore: Why a data science portfolio is essential for job seekers. Selecting projects that align with your target data science roles. Real GitHub examples showcasing best practices. Actionable project ideas you can build right now. Best ways to present your projects and ensure recruiters can find them easily. By the end, you’ll be equipped to craft a compelling portfolio that proves your skills in a tangible way. And when you’re ready for your next career move, remember to upload your CV on DataScience-Jobs.co.uk so that your newly showcased work can be discovered by employers looking for exactly what you have to offer.

Data Science Job Interview Warm‑Up: 30 Real Coding & System‑Design Questions

Data science has become one of the most sought‑after fields in technology, leveraging mathematics, statistics, machine learning, and programming to derive valuable insights from data. Organisations across every sector—finance, healthcare, retail, government—rely on data scientists to build predictive models, understand patterns, and shape strategy with data‑driven decisions. If you’re gearing up for a data science interview, expect a well‑rounded evaluation. Beyond statistics and algorithms, many roles also require data wrangling, visualisation, software engineering, and communication skills. Interviewers want to see if you can slice and dice messy datasets, design experiments, and scale ML models to production. In this guide, we’ll explore 30 real coding & system‑design questions commonly posed in data science interviews. You’ll find challenges ranging from algorithmic coding and statistical puzzle‑solving to the architectural side of building data science platforms in real‑world settings. By practising with these questions, you’ll gain the confidence and clarity needed to stand out among competitive candidates. And if you’re actively seeking data science opportunities in the UK, be sure to visit www.datascience-jobs.co.uk. It’s a comprehensive hub featuring junior, mid‑level, and senior data science vacancies—spanning start‑ups to FTSE 100 companies. Let’s dive into what you need to know.

Negotiating Your Data Science Job Offer: Equity, Bonuses & Perks Explained

Data science has rapidly evolved from a niche specialty to a cornerstone of strategic decision-making in virtually every industry—from finance and healthcare to retail, entertainment, and AI research. As a mid‑senior data scientist, you’re not just running predictive models or generating dashboards; you’re shaping business strategy, product innovation, and customer experiences. This level of influence is why employers are increasingly offering compensation packages that go beyond a baseline salary. Yet, many professionals still tend to focus almost exclusively on base pay when negotiating a new role. This can be a costly oversight. Companies vying for data science talent—especially in the UK, where demand often outstrips supply—routinely offer equity, bonuses, flexible work options, and professional development funds in addition to salary. Recognising these opportunities and effectively negotiating them can have a substantial impact on your total earnings and long-term career satisfaction. This guide explores every facet of negotiating a data science job offer—from understanding equity structures and bonus schemes to weighing crucial perks like remote work and ongoing skill development. By the end, you’ll be well-equipped to secure a holistic package aligned with your market value, your life goals, and the tremendous impact you bring to any organisation.