Postdoctoral Researcher, Quantitative Systems Pharmacology - Fixed Term Contract

Join to apply for the Postdoctoral Researcher, Quantitative Systems Pharmacology – Fix Term Term Contract role at myGwork– LGBTQ+ Business Community. The Clinical Pharmacology and Quantitative Medicine (CPQM) group in Respiratory, Immunology and Inflammation Research Unit, R&D GSK is hiring a Postdoctoral researcher in Quantitative Systems Pharmacology (QSP) to join the CPQM QSP team. The CPQM at GSK is a newly established organization with the remit to become a Centre of Excellence in Model‑Informed Drug Development (MIDD), integrating clinical pharmacology, digital medicine, translational imaging and mechanistic & systems modelling.

This industrial QSP Postdoc position offers scientists with a PhD, MD, PharmD or equivalent doctoral background and experience in mechanistic mathematical modelling the opportunity to work in the pharmaceutical industry, applying systems modelling and computational methodologies to drug discovery and development across GSK’s Respiratory, Immunology and Inflammation portfolio.

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• Build mechanistic mathematical models of biological, physiological and pathophysiological processes to evaluate disease, its pathways and progression as well as drug action; conduct simulations of virtual patients to inform target or asset prioritization and optimal trial design.
  
• Develop and/or utilize state‑of‑the‑art mathematical tools, including non‑linear dynamics, scientific machine learning and/or statistical techniques, to gain insights into causal relationships between individual components of system‑level and drug‑level responses of drug‑target‑biomarker‑disease‑patient interaction.
  
• Identify relevant questions with disease‑area experts and address them using mechanistic and systems modelling.
  
• Collaborate closely with clinicians, biologists, clinical pharmacologists, pharmacometricians, statisticians, AI/ML, imaging, biomarker, genomics scientists and other cross‑matrix colleagues to inform R&D programs and improve understanding of disease mechanisms.
  
• Publish R&D achievements in appropriate scientific journals and promote transparency.
  

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• PhD, MD, or PharmD with experience in mechanistic modelling and simulation and systems biology.
  
• Strong drive to learn rapidly and build knowledge on a drug‑disease system, mechanism, endpoints, progression, prevention, and trial design.
  
• Excellent communication skills and ability to work in multidisciplinary teams with timely delivery of results.
  
• Experience applying modelling in pharmaceutical R&D is a plus.
  
• Experience in Respiratory (e.g., COPD, IPF), Renal (e.g., CKD, nephrotoxicity), Hepatology (e.g., MASH) or Infectious diseases (e.g., HBV) is a plus.
  

The US annual base salary ranges from $87,450 to $145,750, depending on location, experience and market. Additional benefits include an annual bonus, participation in a share‑based long‑term incentive program, health care and other insurance benefits, retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Closing Date for Applications: 7th of December, 2025 (COB). Please submit a cover letter and CV describing how you meet the competencies outlined above.

GSK is an Equal Opportunity Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.

If you require adjustments to our recruitment process, contact or call . Helpline hours: 8:30 am‑12:00 pm, Monday‑Friday.